Web美国 ChemeGen 可提供 10000+ 的活性分子,包括抑制剂、激动剂及新型生命科 学试剂,助力信号通路的研究。ChemeGen 致力于为广大科研人员提供优质的产品和技术服务,专注癌症、炎症等疾病领域的研究。 Web西安齐岳生物科技有限公司生产销售“sphinx31 cas号:1818389-84-2”-“产品名称: sphinx31 cas号:1818389-84-2 物化性质: 分子式:c27h24f3n5o2 分子量:507.51 纯度:98%”,该产品仅用于科研,如果需要请联系我们
Product data sheet - Medkoo
WebAbstract. Purpose : Retinal vascular diseases are treated by intra-ocular injection of anti-VEGFs. SRPK1 inhibitors reduce angiogenic VEGF-A isoforms and choroidal neovascularisation (CNV) in vivo. To address the challenge posed by injections, we developed topical SRPK1 inhibitors with high retinal exposure and low systemic availability. WebDescription SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). … should we pay off mortgage
CAS 1818389-84-2 SPHINX31 - BOC Sciences
WebSPHINX31 is a novel, highly potent, selective, and cell bioactive inhibitor of the serine/arginine-rich protein kinase 1 (SRPK1) with IC50 value of 6 nM. It is selective for … Web7. apr 2024 · SPHINX31 is a potent and selective SRPK1 inhibitor with an IC50 of 5.9 nM. It inhibits the phosphorylation of SRSF1 (serine/arginine-rich splicing factor) and decreases VEGF-A165a isoform expression mRNA. Neovascular eye diseases can be studied using SPHINX31. In a recent study, SPHINX31 was found to have no effect on CCA cell viability … Web25. jan 2024 · Crystal structure of SRPK1 in complex with SPHINX31. Serine/arginine-protein kinase 1 (SRPK1) regulates alternative splicing of VEGF-A to pro-angiogenic isoforms and … sbi taluka office hospet branch ifsc code