WebThe hazard quotient HQ (the risk factor applied to noncarcinogens) relates the dose delivered at the exposure point (the Average Daily Dose ADD) to a toxicological end-point: the reference dose RfD (10.10). Earlier we described how the reference dose RfD is a low-dose end-point, extrapolated from either a NOAEL (Eq. (10.6)) or LOAEL (Eq. (10.7)).An … WebThe quotient approach is designed to be protective, not predictive, and is thus better used for the early tiers or preliminary steps of risk assessments where it can be employed to …
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