Folate receptor endocytosis and trafficking
WebApr 29, 2004 · Folate receptor endocytosis and trafficking. – ScienceOpen. Folate absorption is primarily mediated by a membrane transporter with micro-molar affinities … Web1 day ago · Musalli et al. [31] showed folate receptor-ligand was necessary for caveolae-mediated endocytosis. Although several studies highlighted that clathrin-mediated or caveolin-mediated endocytosis is size-dependent [32, 8], our results did not adhere to the previous findings. Rather multiple uptake mechanisms of CSRBnps were confirmed.
Folate receptor endocytosis and trafficking
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WebNov 16, 2024 · Background The objective of this study was to conduct a bibliometric analysis of the entire field of folate receptor research. Folate receptor is expressed on a wide variety of cancers and certain immune cells. Methods A Web of Science search was performed on folate receptor or folate binding protein (1969-to June 28, 2024). The … WebJun 1, 2007 · Therefore, we have characterized the kinetics of pH-dependent drug release from a model folate-drug conjugate during folate receptor (FR)-mediated endosomal trafficking.
WebFolate receptor-targeted multimodal polymersomes for delivery of quantum dots and doxorubicin to breast adenocarcinoma I.叶酸receptor-targeted交付多聚体多通道量子点 WebMar 6, 2014 · Consequently, the reduction in internalization of DOX-loaded-micelles in cells that had had pretreatment with folic acid was 57% and 26% for KB and MCF-7, …
WebIron-loaded Tf first binds to the Tf receptor (TfR) and enters the cell through clathrin-mediated endocytosis. Inside the cell, Tf is trafficked to early endosomes, delivers iron, and then is subsequently directed to recycling endosomes to be taken back to the cell surface. WebMay 8, 2013 · Additionally, we describe the molecular details of human FR in complex with three clinically prevalent antifolates, pemetrexed (also Alimta), aminopterin, and …
WebNov 10, 2024 · The folate receptor (FR) family plays a crucial role in the uptake of folic acid, commonly known as vitamin B9, which plays a key role in the synthesis of RNA and DNA, aids epigenetic processes and is also involved in cellular proliferation and survival [1, 2].It is overexpressed on proliferating cells which require large amounts of folic acid to …
WebNov 10, 2024 · The folate receptor (FR) family plays a crucial role in the uptake of folic acid, commonly known as vitamin B9, which plays a key role in the synthesis of RNA … caravinagreWebJun 30, 2007 · Folate receptor was over-expressed to a large degree in ovarian neoplasmas that had a high histological grade, advanced stage, and serious histology. A multiple comparison analysis showed that the folate receptor expression of stage IV and omental metastases was significantly higher than that in early stage disease (5). ca ravi kiran ballaWebAccess Online. ezaccess.libraries.psu.edu; Availability. I Want It caravinagre kilikiWebOne actively pursued molecular target in EOC is folate (FR) α, a member of the folate receptor family of high affin-ity folate-binding proteins [1, 2]. FRα is a transmembrane … ca ravine\u0027sWebAug 16, 2024 · 6.7: Receptor-mediated Endocytosis. Just as there is vesicular traffic towards the plasma membrane, either for secretion or for incorporation of membrane lipids or proteins, there can also be vesicular traffic from the plasma membrane. Endocytosis is the process by which a coat protein (usually clathrin) on the cytoplasmic side of the … ca ravi nandan jhaWebFolate absorption is primarily mediated by a membrane transporter with micro-molar affinities for folates. Paradoxically, folates are only present at low nanomolar concentrations in extracellular milieus; membrane folate receptors (FRs) with nanomolar affinities for folates are likely to substantially modulate folate availability for these transporters. … ca ravindra vatsWebApr 1, 2004 · Search life-sciences literature (Over 39 million articles, preprints and more) ca ravindra kore