WebBrn3c-GFP transgenic zebrafish embryos were raised in embryo medium supplemented with varying concentrations of ethanol. Prior to fixation, the larvae were stained with FM 1-43FX (red) to... WebDec 14, 2005 · Brn3a is expressed in RGCs innervating the principal retinothalamic/retinocollicular pathway mediating cortical vision but is not …
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WebJan 18, 2012 · The three members of the Brn3 family of POU-domain transcription factors (Brn3a/Pou4f1, Brn3b/Pou4f2, and Brn3c/Pou4f3) are expressed in overlapping subsets of visual, auditory/vestibular, and somatosensory neurons. Using unmarked Brn3-null alleles and Brn3 conditional alleles in which gene loss is … WebApr 7, 2024 · Additionally, transcriptional levels of RGC-specific indices, including Brn3a, Brn3c, RBPMS, and PCD-related mRNA, such as caspase 8 and GSDMD, were used as indices of nerve injury (Fig. 2 f). These results suggest a neuroprotection role of DMHCA. herb pest control
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WebJun 20, 2024 · Brn3c+ RGC projections can be detected in the Lateral Geniculate Nucleus (LGN), Pretectal Area (PTA) and Superior Colliculus (SC) but also in the thalamic reticular nucleus (TRN), a visual circuit station that was not previously described to receive retinal input. Most Brn3c+ neurons of the brain are confined to the pretectum and the dorsal ... WebMar 14, 2024 · Data indicate that Brn3 transcription factors Brn3b affects Brn3a and Brn3c positive Retinal Ganglion Cells (RGCs) in cell autonomous and non-cell autonomous fashion. The results demonstrated a critical role for Brn3a in generating dorsal root ganglia sensory neuron diversity and regulating sensory afferent projections to the central targets. WebJun 9, 2024 · Xiang et al. (1995) showed that BRN3B has 2 closely related homologs, termed BRN3A (601632) and BRN3C (602460). The 3 genes share intron/exon structures but map to distinct chromosomes. Xiang et al. (1995) analyzed the expression patterns of brn3a, brn3b, and brn3c in fetal and adult mouse retina and brain. Antibodies to brn3b … matt callaway volleyball